Article
Colony-stimulating factor-1 plays a major role in the development of reproductive function in male mice.
Molecular endocrinology (Baltimore, Md.) - 1 Oct 1997
Cohen P E, Hardy M P, Pollard J W
Abstract excerpt
Colony-stimulating factor-1 (CSF-1) is the principal regulator of cells of the mononuclear phagocytic lineage that includes monocytes, tissue macrophages, microglia, and osteoclasts. Macrophages are found throughout the reproductive tract of both males and females and have been proposed to act as regulators of fertility at several levels. Mice homozygous for the osteopetrosis mutation (csfm[op]) lack CSF-1 and,...
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