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Article

Identification and characterization of a DR4-restricted T cell epitope within chlamydia heat shock protein 60

1 Sept 1997

Abstract excerpt

An epitope within the 60 kD Chlamydia trachomatis heat shock protein (hsp) 60, recognized by a HLA-DRB1*0401-restricted T cell clone from a reactive arthritis patient, has been characterized. Stimulatory peptides contained a nine amino acid sequence (residues 38-46) predicted by algorithm to confer strong binding to DRB1*0401, with valine in the P1 position. The overall length of the peptide was critical for...

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Identifiers

PMID: 9328119
DOI: 10.1046/j.1365-2249.1997.4711371.x

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