Molecular characterisation of the NSP4 gene of group A human rotavirus G2P[4] strains circulating in São Paulo, Brazil, from 1994 and 2006 to 2010.

doi:10.1590/0074-02760150199

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Molecular characterisation of the NSP4 gene of group A human rotavirus G2P[4] strains circulating in São Paulo, Brazil, from 1994 and 2006 to 2010.

Memorias do Instituto Oswaldo Cruz - 1 Sept 2015

Bertol Jéssica Wildgrube, Fregolente Maria Clara Duarte, Caruzo Thabata Alessandra Ramos, Silva Márcio José da, Munford Veridiana, Sáfadi Marco Aurélio Palazzi, Rácz Maria Lucia, Gatti Maria Silvia Viccari

Abstract excerpt

Group A human rotaviruses (HuRVA) are causative agents of acute gastroenteritis. Six viral structural proteins (VPs) and six nonstructural proteins (NSPs) are produced in RV-infected cells. NSP4 is a diarrhoea-inducing viral enterotoxin and NSP4 gene analysis revealed at least 15 (E1-E15) genotypes. This study analysed the NSP4 genetic diversity of HuRVA G2P[4] strains collected in the state of São Paulo (SP)...

Topics

Adult
Amino Acid Sequence
Antigens, Viral
Base Sequence
Brazil
Child
Feces
Genetic Linkage
Genetic Variation
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glycoproteins

Humans

Immunoenzyme Techniques

Molecular Sequence Data

Phylogeny

RNA, Viral

Reverse Transcriptase Polymerase Chain Reaction

Rotavirus

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Identifiers

PMID: 26517658
DOI: 10.1590/0074-02760150199
PMCID: PMC4667582

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