Article
Molecular characterization of the NSP4 gene of human group A rotavirus samples from the West Central region of Brazil.
Memorias do Instituto Oswaldo Cruz - 1 May 2008
Tavares Talissa de Moraes, Brito Wilia Marta Elsner Diederichsen de, Fiaccadori Fabíola Souza, Freitas Erika Regina Leal de, Parente Juliana Alves, Costa Paulo Sérgio Sucasas da, Giugliano Loreny Gimenes, Andreasi Márcia Sueli Assis, Soares Célia Maria Almeida, Cardoso Divina das Dôres de Paula
Abstract excerpt
Nonstructural protein 4 (NSP4), encoded by group A rotavirus genome segment 10, is a multifunctional protein and the first recognized virus-encoded enterotoxin. The NSP4 gene has been sequenced, and five distinct genetic groups have been described: genotypes A-E. NSP4 genotypes A, B, and C have been detected in humans. In this study, the NSP4-encoding gene of human rotavirus strains of different G and P genotypes...
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