Article
A novel apolipoprotein C-III variant, apoC-III(Gln38-->Lys), associated with moderate hypertriglyceridemia in a large kindred of Mexican origin.
Journal of lipid research - 1 Sept 1997
Pullinger C R, Malloy M J, Shahidi A K, Ghassemzadeh M, Duchateau P, Villagomez J, Allaart J, Kane J P
Abstract excerpt
Apolipoprotein C-III (apoC-III) is a major protein component of very low density lipoproteins (VLDL), chylomicrons, and a minor component of high density lipoproteins (HDL). Studies of naturally occurring human variants of apoC-III will help in adding to our understanding of the physiological function of this apolipoprotein. Using isoelectric focusing (IEF) of VLDL fractions we screened over 2500 lipid clinic...
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