Article
Maturity-onset diabetes of the young due to a mutation in the hepatocyte nuclear factor-4 alpha binding site in the promoter of the hepatocyte nuclear factor-1 alpha gene.
Diabetes - 1 Oct 1997
Gragnoli C, Lindner T, Cockburn B N, Kaisaki P J, Gragnoli F, Marozzi G, Bell G I
Abstract excerpt
Recent studies have shown that mutations in the transcription factor hepatocyte nuclear factor (HNF)-1 alpha are the cause of one form of maturity-onset diabetes of the young (MODY3). These studies have identified mutations in the mRNA and protein coding regions of this gene that result in the sy...
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