Article
Complement activation by heparin-protamine complexes during cardiopulmonary bypass: effect of C4A null allele.
The Journal of thoracic and cardiovascular surgery - 1 Sept 1997
Shastri K A, Logue G L, Stern M P, Rehman S, Raza S
Abstract excerpt
OBJECTIVES: The first objective was to determine the effect of inherited differences in the classic pathway complement protein C4 on complement activation by heparin-protamine complexes in cardiac surgery. Specifically, we hypothesized that patients with heterozygous C4A null phenotype (A0BB), who have decreased amounts of C4A, may have increased complement activation because of reduced clearance of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.