Article
Treatment of congenital fibrinogen deficiency: overview and recent findings.
Vascular health and risk management - 1 Jan 2009
Tziomalos Konstantinos, Vakalopoulou Sofia, Perifanis Vassilios, Garipidou Vassilia
Abstract excerpt
Afibrinogenemia is a rare bleeding disorder with an estimated prevalence of 1:1,000,000. It is an autosomal recessive disease resulting from mutations in any of the 3 genes that encode the 3 polypeptide chains of fibrinogen and are located on the long arm of chromosome 4. Spontaneous bleeding, bl...
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