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Article

Mechanisms of multidrug transporters

1 Aug 1997

Abstract excerpt

Drug resistance, mediated by various mechanisms, plays a crucial role in the failure of the drug-based treatment of various infectious diseases. As a result, these infectious diseases re-emerge rapidly and cause many victims every year. Another serious threat is imposed by the development of multidrug resistance (MDR) in eukaryotic (tumor) cells, where many different drugs fail to perform their therapeutic...

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PMID: 9299702
DOI: 10.1111/j.1574-6976.1997.tb00345.x

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