Article
Androgen-regulated gene expression in prostate cancer.
Seminars in cancer biology - 1 Feb 1997
Trapman J, Cleutjens K B
Abstract excerpt
Androgen-regulated gene expression is mediated by the ligand-activated androgen receptor. Androgen receptor target genes contain in the regulatory regions one or more androgen response elements. Development of the male urogenital tract, including the prostate, depends on an activated androgen receptor. Similarly, growth of the majority of prostate cancers is androgen-dependent. Therefore, endocrine therapy, aimed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
