Modulation of the dihydropyridine-sensitive calcium channels in Drosophila by a phospholipase C-mediated pathway.

doi:10.1002/(sici)1097-4695(199709)33:3<265::aid-neu5>3.0.co;2-#

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Article

Modulation of the dihydropyridine-sensitive calcium channels in Drosophila by a phospholipase C-mediated pathway.

Journal of neurobiology - 1 Sept 1997

Gu G G, Singh S

Abstract excerpt

Disruption of phospholipase C-beta (PLC) by the norpA mutations of Drosophila renders flies blind by affecting the light-evoked photoreceptor potential. We report here that the norpA-coded PLC modulates the 1,4-dihydropyridine (DHP)-sensitive Ca2+ channels in larval muscles. The DHP-sensitive cur...

Topics

Animals
Calcium Channel Blockers
Calcium Channels
Diglycerides
Dihydropyridines
Drosophila
Enzyme Inhibitors
Female
Larva
Male
Muscles
Mutation
Protein Kinase C
Type C Phospholipases

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