Article
Tissue-specific expression of phospholipase C encoded by the norpA gene of Drosophila melanogaster.
The Journal of biological chemistry - 25 Jul 1993
Zhu L, McKay R R, Shortridge R D
Abstract excerpt
Mutations in the norpA gene of Drosophila melanogaster severely affect the light-evoked photoreceptor potential with strong mutations rendering the fly blind. Molecular cloning of the norpA gene revealed that it encodes phosphatidylinositol-specific phospholipase C, which enzymes play a pivotal role in one of the largest classes of signaling pathways known. We have used Northern analysis, Western blots,...
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