Mutations of thyrotropin receptor gene.

doi:10.1007/s001090050141

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Article

Mutations of thyrotropin receptor gene.

Journal of molecular medicine (Berlin, Germany) - 1 Aug 1997

Porcellini A, Fenzi G, Avvedimento E V

Abstract excerpt

Thyrotropin is the primary pituitary hormone which stimulates the growth and differentiation of thyroid cells. TSH binds a specific receptor present in the plasma membrane of thyroid cells and signals the G protein transducers, which activate different effectors, mainly adenyl cyclase and phospho...

Topics

Adenoma
Amino Acid Sequence
Cyclic AMP
Cyclic AMP Response Element-Binding Protein
GTP-Binding Proteins
Humans
Molecular Sequence Data
Mutation
Receptors, Thyrotropin
Signal Transduction
Thyroid Neoplasms

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