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Article

Mutations of thyrotropin receptor gene.

Journal of molecular medicine (Berlin, Germany) - 1 Aug 1997

Porcellini A, Fenzi G, Avvedimento E V

Abstract excerpt

Thyrotropin is the primary pituitary hormone which stimulates the growth and differentiation of thyroid cells. TSH binds a specific receptor present in the plasma membrane of thyroid cells and signals the G protein transducers, which activate different effectors, mainly adenyl cyclase and phospholipase C. The TSH receptor belongs to a broad class of receptors known as seven-loop receptors because they contain a...

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Identifiers

PMID: 9297624
DOI: 10.1007/s001090050141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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