Article
Testing candidate loci on chromosomes 1 and 6 for genetic linkage to Peutz-Jeghers' disease.
Annals of human genetics - 1 Sept 1996
Tomlinson I P, Olschwang S, Abelovitch D, Nakamura Y, Bodmer W F, Thomas G, Markie D
Abstract excerpt
Peutz-Jeghers' syndrome (PJS) is a disease with autosomal dominant inheritance, which is characterised by gastrointestinal hamartomata and characteristic melanin pigmentation. Three candidate sites for a PJS locus have recently been proposed, chromosomes 1p31-p32, 6q25 and 6p11-cen. At the first...
Topics
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 6
- Female
- France
- Genotype
- Humans
- In Situ Hybridization, Fluorescence
- Israel
- Japan
- Karyotyping
- Lod Score
- Male
- Pedigree
- Peutz-Jeghers Syndrome
- United Kingdom