Article
Cell and matrix reactions at titanium implants in surgically prepared rat tibiae.
The International journal of oral & maxillofacial implants - 1 Jan 2000
Masuda T, Salvi G E, Offenbacher S, Felton D A, Cooper L F
Abstract excerpt
The tissue response of rat tibiae to the surgical placement of commercially pure titanium implants was examined at 2, 6, 10, and 28 days. The transcortical placement of 1.5-mm x 2-mm implants resulted in the apposition of threaded implant surfaces within cortical and cancellous regions of the tibia. In all regions, evidence of bone formation was obtained through pre-embedding fracture of the implant from the bone...
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