Salmonella typhi mutants defective in anaerobic respiration are impaired in their ability to replicate within epithelial cells.

doi:10.1099/00221287-143-8-2665

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Article

Salmonella typhi mutants defective in anaerobic respiration are impaired in their ability to replicate within epithelial cells.

Microbiology (Reading, England) - 1 Aug 1997

Contreras Inés, Toro Cecilia S, Troncoso Gonzalo, Mora Guido C

Abstract excerpt

By using MudJ (Kan, lac)-directed operon fusion technology, mutants of Salmonella typhi whose gene expression is induced under anaerobic growth conditions were isolated. Characterization of their phenotypes and regulatory properties revealed that two of the mutants were unable to use nitrate as a...

Topics

Anaerobiosis
Bacterial Proteins
Cells, Cultured
Chlorates
Drug Resistance, Microbial
Electron Transport
Epithelial Cells
Epithelium
Escherichia coli Proteins
Iron-Sulfur Proteins
Membrane Proteins
Mutagenesis, Insertional
Mutation
Nitrates
Operon
Recombinant Fusion Proteins
Salmonella typhi

Source

Open in PubMed

Identifiers

PMID: 9274020
DOI: 10.1099/00221287-143-8-2665

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9274020-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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