Article
Geographic distribution of French-Canadian low-density lipoprotein receptor gene mutations in the Province of Quebec.
Clinical genetics - 1 Jul 1997
Vohl M C, Moorjani S, Roy M, Gaudet D, Torres A L, Minnich A, Gagné C, Tremblay G, Lambert M, Bergeron J, Couture P, Perron P, Blaichman S, Brun L D, Davignon J, Lupien P J, Després J P
Abstract excerpt
A total of 35 homozygous and 1320 heterozygous patients with familial hypercholesterolemia (FH) was screened for the presence of six low-density lipoprotein receptor (LDLR) gene mutations previously reported among French-Canadians. The geographic distribution of patients' birthplaces and the rela...
Topics
- Exons
- Gene Frequency
- Heterozygote
- Homozygote
- Humans
- Hyperlipoproteinemia Type II
- Mutation
- Point Mutation
- Prevalence
- Quebec
- Receptors, LDL
- Sequence Deletion