Article
Genealogy and regional distribution of lipoprotein lipase deficiency in French-Canadians of Quebec.
Human biology - 1 Feb 1993
Dionne C, Gagné C, Julien P, Murthy M R, Roederer G, Davignon J, Lambert M, Chitayat D, Ma R, Henderson H
Abstract excerpt
Lipoprotein lipase (LPL) deficiency, an autosomal recessive disorder causing chylomicronemia, has a high prevalence in the French-Canadian population of Quebec. The molecular basis of LPL deficiency has been defined, and two major mutations have been shown to have an uneven geographic distributio...
Topics
- France
- Genetic Carrier Screening
- Genetic Testing
- Humans
- Hyperlipoproteinemia Type I
- Mutation
- Pedigree
- Prevalence
- Quebec
- Residence Characteristics