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Article

Sequence and expression of a novel member (LTBP‐4) of the family of latent transforming growth factor‐<i>β</i> binding proteins

14 Jul 1997

Abstract excerpt

Overlapping cDNA clones from human heart and melanoma libraries were used to establish the 1587-residue sequence of a novel protein (LTBP-4) belonging to the family of extracellular microfibrillar proteins which also bind transforming growth factor-beta. LTBP-4 consists of 20 EG modules, 17 of them with a consensus sequence for calcium binding, 4 TB modules with 8 cysteines and several proline-rich regions....

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PMID: 9271198
DOI: 10.1016/s0014-5793(97)00685-6

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