Article
Resistance to radiation-induced apoptosis in Burkitt's lymphoma cells is associated with defective ceramide signaling.
Cancer research - 15 Aug 1997
Michael J M, Lavin M F, Watters D J
Abstract excerpt
Increased sensitivity to ionizing radiation has been shown to be due to defects in double-strand break repair and mutations in the proteins that detect DNA damage. However, it is now recognized that the cellular radiation response is complex and that radioresistance/radiosensitivity may also be regulated at different levels in the radiation signal transduction pathway. Here, we describe a direct relationship...
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