Article
Detection of chromosomes and estimation of aneuploidy in human spermatozoa using fluorescence in-situ hybridization
1 Jul 1997
Abstract excerpt
The development and application of fluorescence in-situ hybridization (FISH) has opened the way for comprehensive studies on numerical chromosome abnormalities in human spermatozoa. FISH can be rapidly applied to large numbers of spermatozoa and thus overcomes the major limitation of karyotyping spermatozoa after penetration of zona-free hamster oocytes. The simultaneous hybridization of two or more...
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