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Sperm and Blastomere Aneuploidy Detection in Reproductive Genetics and Medicine

1 Mar 2005

Abstract excerpt

The use of multiple probes in fluorescence in situ hybridization (FISH) permits the simultaneous analysis of several chromosomes in both blastomeres and spermatozoa. Preimplantation genetic diagnosis (PGD) for aneuploidy provides information on embryonic chromosomal status, enabling the selection of embryos carrying aneuploid condition. This strategy directly affects implantation, as documented for patients with...

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PMID: 15749998
DOI: 10.1369/jhc.4b6434.2005

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