Article
Yeast 5-aminolevulinate synthase provides additional chlorophyll precursor in transgenic tobacco.
The Plant journal : for cell and molecular biology - 1 Jul 1997
Zavgorodnyaya A, Papenbrock J, Grimm B
Abstract excerpt
Synthesis of the tetrapyrrole precursor 5-aminolevulinate (ALA) in plants starts with glutamate and is a tRNA-dependent pathway consisting of three enzymatic steps localized in plastids. In animals and yeast, ALA is formed in a single step from succinyl CoA and glycine by aminolevulinate synthase (ALA-S) in mitochondria. A gene encoding a fusion protein of yeast ALA-S with an aminoterminal transit sequence for...
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