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Article

Mitochondrial succinic-semialdehyde dehydrogenase of the gamma-aminobutyrate shunt is required to restrict levels of reactive oxygen intermediates in plants.

Proceedings of the National Academy of Sciences of the United States of America - 27 May 2003

Bouché Nicolas, Fait Aaron, Bouchez David, Møller Simon G, Fromm Hillel

Abstract excerpt

The gamma-aminobutyrate (GABA) shunt is a metabolic pathway that bypasses two steps of the tricarboxylic acid cycle, and it is present in both prokaryotes and eukaryotes. In plants the pathway is composed of the calcium/calmodulin-regulated cytosolic enzyme glutamate decarboxylase and the mitochondrial enzymes GABA transaminase and succinic-semialdehyde dehydrogenase (SSADH). The activity of the GABA shunt in...

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PMID: 12740438
DOI: 10.1073/pnas.1037532100
PMCID: PMC164534

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