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Article

Overexpression of HEMA1 encoding glutamyl-tRNA reductase.

Journal of plant physiology - 15 Aug 2011

Schmied Judith, Hedtke Boris, Grimm Bernhard

Abstract excerpt

5-Aminolevulinic acid (ALA) synthesis has been shown to be the rate limiting step of tetrapyrrole biosynthesis. Glutamyl-tRNA reductase (GluTR) is the first committed enzyme of plant ALA synthesis and is controlled by interacting regulators, such as heme and the FLU protein. Induced inactivation of the HEMA1 gene encoding GluTR by RNAi expression in tobacco resulted in a reduced activity of Mg chelatase and Fe...

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PMID: 21272955
DOI: 10.1016/j.jplph.2010.12.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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