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Article

Epigenetic phenomena in filamentous fungi: useful paradigms or repeat-induced confusion?

Trends in genetics : TIG - 1 Aug 1997

Selker E U

Abstract excerpt

Epigenetic mechanisms can serve as genome defense systems. In haploid nuclei of special sexual cells of fungi, such as Neurospora and Ascobolus, duplicated genes are silenced by hypermutation, DNA methylation, or both. In some cases, DNA introduced into the genome of Neurospora cells by transformation can also inhibit homologous genes by a silencing mechanism that does not involve DNA pairing or methylation and...

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PMID: 9260514
DOI: 10.1016/s0168-9525(97)01201-8

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