Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic association of juvenile absence epilepsy with a GluR5 kainate receptor gene (GRIK1) polymorphism.

American journal of medical genetics - 25 Jul 1997

Sander T, Hildmann T, Kretz R, Fürst R, Sailer U, Bauer G, Schmitz B, Beck-Mannagetta G, Wienker T F, Janz D

Abstract excerpt

Juvenile absence epilepsy (JAE) is a common subtype of idiopathic generalized epilepsy (IGE). Hereditary factors play a major role in its etiology. The important function of glutamate receptors (GluRs) in excitatory neurotransmission, synaptic plasticity, and neurodevelopment suggests their involvement in epileptogenesis. A tetranucleotide repeat polymorphism in the non-coding region of the kainate-selective...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Disease Susceptibility

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Genotype

Share to Haplotypes

Share to Microsatellite Repeats

Share to Pedigree

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 9259378

Genes

GRIK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic association of juvenile absence epilepsy with a GluR5 kainate receptor gene (GRIK1) polymorphism.PMID 9259378Read ↗

Sequencing of the GRIK1 gene in patients with juvenile absence epilepsy does not reveal mutations affecting receptor structure.Semantic proximity Read ↗

Association study of GRIK1 gene polymorphisms in schizophrenia: case-control and family-based studies.Semantic proximity Read ↗

Kainate receptor subunit 1 (GRIK1) risk variants and GRIK1 deficiency were detected in the Indian ADHD probands.Semantic proximity Read ↗

Clustered mutations in the GRIK2 kainate receptor subunit gene underlie diverse neurodevelopmental disorders.Semantic proximity Read ↗

1p34.3 deletion involving GRIK3: Further clinical implication of GRIK family glutamate receptors in the pathogenesis of developmental delay.Semantic proximity Read ↗

Association study of polymorphisms in the GluR5 kainate receptor gene (GRIK1) with schizophrenia.Semantic proximity Read ↗

Wide-ranging behavioral dysfunction in two mouse models of pathological human variants in the <i>GRIK2</i> kainate receptor geneSemantic proximity Read ↗

Role of GRM4 in idiopathic generalized epilepsies analysed by genetic association and sequence analysis.Semantic proximity Read ↗

The phenotypic spectrum related to the human epilepsy susceptibility gene "EJM1".Semantic proximity Read ↗

Glutamate AMPA receptor subunit 1 gene (GRIA1) and DSM-IV-TR schizophrenia: a pilot case-control association study in an Italian sample.Semantic proximity Read ↗

Clinical and therapeutic significance of genetic variation in the GRIN gene family encoding NMDARs.Semantic proximity Read ↗

Candidate gene analysis of the human metabotropic glutamate receptor type 4 (GRM4) in patients with juvenile myoclonic epilepsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.