Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Simian virus-40 large-T antigen binds p53 in human mesotheliomas.

Nature medicine - 1 Aug 1997

Carbone M, Rizzo P, Grimley P M, Procopio A, Mew D J, Shridhar V, de Bartolomeis A, Esposito V, Giuliano M T, Steinberg S M, Levine A S, Giordano A, Pass H I

Abstract excerpt

We found that simian virus 40 (SV40) induces mesotheliomas in hamsters and that 60% of human mesotheliomas contain and express SV40 sequences, results now confirmed by others [ref. 3-5, and presentations by D. Griffiths & R. Weiss, F. Galateau-SallE, and H.I.P. at "Simian virus 40: A possible hum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Polyomavirus Transforming
Share to Gene Expression Regulation, Neoplastic
Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Mutation

Share to Protein Binding

Share to Tumor Cells, Cultured

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 9256284
DOI: 10.1038/nm0897-908

Genes

SAG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9256284-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Simian virus-40 large-T antigen binds p53 in human mesotheliomas.PMID 9256284Read ↗

SV40 and human mesotheliomaSemantic proximity Read ↗

SV40 Oncoproteins Enhance Asbestos-Induced DNA Double-Strand Breaks and Abrogate Senescence in Murine Mesothelial CellsSemantic proximity Read ↗

Human mesothelial cells are unusually susceptible to simian virus 40-mediated transformation and asbestos cocarcinogenicitySemantic proximity Read ↗

The role of environmental carcinogens, viruses and genetic predisposition in the pathogenesis of mesothelioma.Semantic proximity Read ↗

Evidence against a Role for SV40 in Human MesotheliomaSemantic proximity Read ↗

Biological agents involved in malignant mesothelioma: relevance as biomarkers or therapeutic targets.Semantic proximity Read ↗

A Novel SV40 TAg Transgenic Model of Asbestos-Induced Mesothelioma: Malignant Transformation Is Dose DependentSemantic proximity Read ↗

Mesotheliomas in Genetically Engineered Mice Unravel Mechanism of Mesothelial Carcinogenesis.Semantic proximity Read ↗

New developments about the association of SV40 with human mesotheliomaSemantic proximity Read ↗

Advances in the molecular biology of malignant mesothelioma.Semantic proximity Read ↗

Biological basis for novel mesothelioma therapiesSemantic proximity Read ↗

Cellular and molecular parameters of mesotheliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.