Article
Ketolides lack inducibility properties of MLS(B) resistance phenotype.
The Journal of antimicrobial chemotherapy - 1 Jul 1997
Bonnefoy A, Girard A M, Agouridas C, Chantot J F
Abstract excerpt
Ketolides belong to a new class of semi-synthetic 14-membered-ring macrolides, which differ from erythromycin A by having a 3-keto group instead of the neutral sugar L-cladinose. The ability of these molecules and their L-cladinose counterparts to induce MLS(B) resistance in staphylococci (one strain) and streptococci (two strains) was investigated using a disc agar susceptibility method as well as measuring...
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