Article
Non-inducible, mainly cell-associated beta-lactamase from Nocardia asteroides strain 108.
The Journal of antimicrobial chemotherapy - 1 Jul 1997
Scopetti F, Fattorini L, Franceschini N, Amicosante G, Orefici G
Abstract excerpt
The beta-lactamase of the soil-borne strain 108 (parental strain) of Nocardia asteroides is a non-inducible enzyme mainly associated with the cells; it can be efficiently extracted by ultrasonication and SDS treatment. Crude enzyme preparations showed penicillinase and cephalosporinase activity. The kinetics of beta-lactamase production and in-vitro susceptibility to combinations of beta-lactam antibiotics plus...
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