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Article

Sequence diversity and molecular evolution of the merozoite surface antigen 2 of Plasmodium falciparum.

Journal of molecular evolution - 1 Aug 1997

Felger I, Marshal V M, Reeder J C, Hunt J A, Mgone C S, Beck H P

Abstract excerpt

Eleven new alleles of the Plasmodium falciparum merozoite surface antigen 2 (MSA2) from Papua New Guinea were analyzed by direct sequencing of polymerase chain reaction (PCR) products. We have used the sequence information to trace the molecular evolution of MSA2. The repeats of ten alleles belonging to the 3D7 allelic family differed considerably in size, nucleotide sequence, and repeat copy number. In the...

Topics

Amino Acid Sequence
Animals
Antigens, Protozoan
Antigens, Surface
Base Sequence
Codon
Consensus Sequence
DNA, Protozoan
Evolution, Molecular
Genetic Variation
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasmodium falciparum

Polymorphism, Single-Stranded Conformational

Protozoan Proteins

Source

Identifiers

PMID: 9236275
DOI: 10.1007/pl00006215

Genes

NNT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-9236275-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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