Article
Fusion competence of myoblasts rendered genetically null for N-cadherin in culture.
The Journal of cell biology - 28 Jul 1997
Charlton C A, Mohler W A, Radice G L, Hynes R O, Blau H M
Abstract excerpt
Myoblast fusion is essential to muscle tissue development yet remains poorly understood. N-cadherin, like other cell surface adhesion molecules, has been implicated by others in muscle formation based on its pattern of expression and on inhibition of myoblast aggregation and fusion by antibodies or peptide mimics. Mice rendered homozygous null for N-cadherin revealed the general importance of the molecule in...
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