Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modulation of Myoblast Fusion by Caveolin-3 in Dystrophic Skeletal Muscle Cells: Implications for Duchenne Muscular Dystrophy and Limb-Girdle Muscular Dystrophy-1C

12 Aug 2003

Abstract excerpt

Caveolae are vesicular invaginations of the plasma membrane. Caveolin-3 is the principal structural component of caveolae in skeletal muscle cells in vivo. We have recently generated caveolin-3 transgenic mice and demonstrated that overexpression of wild-type caveolin-3 in skeletal muscle fibers is sufficient to induce a Duchenne-like muscular dystrophy phenotype. In addition, we have shown that caveolin-3 null...

Topics

Join the communities discussing this publication.

Cardiomyopathy and Myosin Studies
Caveolin-1 and cellular processes
Metabolism, Diabetes, and Cancer

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 14517320
DOI: 10.1091/mbc.e03-03-0161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modulation of Myoblast Fusion by Caveolin-3 in Dystrophic Skeletal Muscle Cells: Implications for Duchenne Muscular Dystrophy and Limb-Girdle Muscular Dystrophy-1CPMID 14517320Read ↗

Transgenic overexpression of caveolin-3 in skeletal muscle fibers induces a Duchenne-like muscular dystrophy phenotype.Semantic proximity Read ↗

Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities.Semantic proximity Read ↗

Loss of caveolin-3 induced by the dystrophy-associated P104L mutation impairs L-type calcium channel function in mouse skeletal muscle cells.Semantic proximity Read ↗

A Role for Caveolin-3 in the Pathogenesis of Muscular Dystrophies.Semantic proximity Read ↗

Caveolae and caveolin-3 in muscular dystrophy.Semantic proximity Read ↗

Caveolinopathies: from the biology of caveolin-3 to human diseases.Semantic proximity Read ↗

Caveolinopathies: translational implications of caveolin-3 in skeletal and cardiac muscle disorders.Semantic proximity Read ↗

Zebrafish as a model for caveolin-associated muscle disease; caveolin-3 is required for myofibril organization and muscle cell patterningSemantic proximity Read ↗

Caveolin-3 deficiency causes muscle degeneration in mice.Semantic proximity Read ↗

Mutations in the caveolin-3 gene cause autosomal dominant limb-girdle muscular dystrophy.Semantic proximity Read ↗

BIN1 overexpression rescues cardiac but not skeletal muscle defects in a mouse model of caveolinopathySemantic proximity Read ↗

Caveolin-3 deficiency associated with the dystrophy P104L mutation impairs skeletal muscle mitochondrial form and function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.