Article
Constitutive expression of a CD44 variant isoform on T cells facilitates regaining of immunocompetence in allogeneic bone marrow transplantation.
Blood - 15 Jul 1997
Zöller M, Schmidt A, Denzel A, Moll J
Abstract excerpt
Constitutive expression of a rat CD44 variant isoform, rCD44v4-v7, on murine T cells accelerates immune responsiveness. Because prolonged immunodeficiency can be a major drawback in allogeneic bone marrow transplantation, we considered it of special interest to see whether repopulation of lethall...
Topics
- Animals
- Bone Marrow Transplantation
- Crosses, Genetic
- Genetic Variation
- Hyaluronan Receptors
- Immunocompetence
- Lymph Nodes
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Transgenic
- Rats
- Recombinant Proteins
- Spleen
- T-Lymphocyte Subsets
- T-Lymphocytes
- Thymus Gland
- Time Factors