Article
An expanded histatin gene polymorphism and test of a possible disease resistant phenotype.
Human mutation - 1 Jan 1997
Araki M, Anstey N M, Mwaikambo E D, Dua A, Amberger E, Azen E A
Abstract excerpt
Histatins are small molecular weight salivary proteins that are important in the non-immune host defense system. Two frequent cis-linked coding-change mutations were previously described in exon 5 of the HIS2 gene of Blacks. The polymorphic mutant allele was termed HIS2(2) and the wild-type allele HIS2(1). We here describe two new non-coding change polymorphisms of the HIS2 gene: a deletion in intron 5 (7183-7198...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.