Article
Oligonucleotide micro-arrays for identification of unknown mutations: how far from reality?
Human mutation - 1 Jan 1997
Ginot F
Abstract excerpt
The present review examines critically what has been published on oligonucleotide micro-arrays, from the point of view of detection of unknown mutations. We will first demonstrate the theoretical power of this new technique, and then argue that it is experimentally realistic. However, technical difficulties remain, and the proposed solutions for controlling the hybridisation specificity and for manufacturing the...
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