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Article

Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA.

Science (New York, N.Y.) - 18 Jul 1997

Long R M, Singer R H, Meng X, Gonzalez I, Nasmyth K, Jansen R P

Abstract excerpt

Cell divisions that produce progeny differing in their patterns of gene expression are key to the development of multicellular organisms. In the budding yeast Saccharomyces cerevisiae, mother cells but not daughter cells can switch mating type because they selectively express the HO endonuclease...

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Identifiers

PMID: 9219698
DOI: 10.1126/science.277.5324.383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9219698-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA.PMID 9219698Read ↗

Identification of asymmetrically localized determinant, Ash1p, required for lineage-specific transcription of the yeast HO gene.Semantic proximity Read ↗

The protein kinase Pho85 is required for asymmetric accumulation of the Ash1 protein in Saccharomyces cerevisiae.Semantic proximity Read ↗

ASH1 mRNA localization in three acts.Semantic proximity Read ↗

The Khd1 protein, which has three KH RNA-binding motifs, is required for proper localization of ASH1 mRNA in yeast.Semantic proximity Read ↗

Ash1, a daughter cell-specific protein, is required for pseudohyphal growth of Saccharomyces cerevisiae.Semantic proximity Read ↗

Cotranscriptional recruitment of She2p by RNA pol II elongation factor Spt4-Spt5/DSIF promotes mRNA localization to the yeast bud.Semantic proximity Read ↗

She3p possesses a novel activity required for ASH1 mRNA localization in Saccharomyces cerevisiae.Semantic proximity Read ↗

Ash1 protein, an asymmetrically localized transcriptional regulator, controls filamentous growth and virulence of Candida albicans.Semantic proximity Read ↗

Repressive chromatin affects factor binding at yeast HO (homothallic switching) promoter.Semantic proximity Read ↗

Quality control of MATa1 splicing and exon skipping by nuclear RNA degradation.Semantic proximity Read ↗

The Rts1 regulatory subunit of PP2A phosphatase controls expression of the HO endonuclease via localization of the Ace2 transcription factor.Semantic proximity Read ↗

Posttranscriptional regulation of HO expression by the Mkt1-Pbp1 complex.Semantic proximity Read ↗

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