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Article

Advanced paternal age: How old is too old?

13 Sept 2006

Abstract excerpt

Average paternal age in the UK is increasing. The public health implications of this trend have not been widely anticipated or debated. This commentary aims to contribute to such a debate. Accumulated chromosomal aberrations and mutations occurring during the maturation of male germ cells are thought to be responsible for the increased risk of certain conditions with older fathers. Growing evidence shows that the...

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PMID: 16973530
DOI: 10.1136/jech.2005.045179

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