Myotonic dystrophy: molecular and cellular consequences of expanded DNA repeats are elusive.

doi:10.1023/a:1005396420442

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Article

Myotonic dystrophy: molecular and cellular consequences of expanded DNA repeats are elusive.

Journal of inherited metabolic disease - 1 Jun 1997

Strong P N, Brewster B S

Abstract excerpt

The mutation in the myotonic dystrophy (DM) gene is an expansion in a triplet (CTG) repeat in the 3' untranslated region of a novel gene that partially encodes a serine-threonine protein kinase (DMPK), with closest sequence homology to a small subgroup of protein kinases involved in the control o...

Topics

Animals
Gene Expression
Humans
Mutation
Myotonic Dystrophy
Protein Serine-Threonine Kinases
Trinucleotide Repeats

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