Effects of midazolam on the differentiation of murine myeloid leukemia cells.

doi:10.1159/000239578

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Article

Effects of midazolam on the differentiation of murine myeloid leukemia cells.

Chemotherapy - 1 Jan 2000

Mak N K, Szeto Y Y, Fung M C, Leung K N, Kwan S K

Abstract excerpt

The effects of midazolam (MID) on the in vitro growth and differentiation of two murine myeloid leukemia WEHI 3B (JCS) and M1 cells were studied. MID inhibits the proliferation of both M1 and JCS cells in a dose-dependent manner. At the concentration of 10 micrograms/ml, MID was found to induce b...

Topics

Anesthetics, Intravenous
Animals
Cell Differentiation
Cell Division
Drug Evaluation, Preclinical
Flow Cytometry
Leukemia, Myeloid
Mice
Midazolam
Phagocytosis
Phenotype
RNA, Messenger

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