Article
Cloning and Characterization of a Testis‐Specific, Developmentally Regulated A‐Kinase‐Anchoring Protein (Takap‐80) Present on the Fibrous Sheath of Rat Sperm
1 Jun 1997
Abstract excerpt
cAMP is important for the initiation of mammalian sperm motility. Previously we established that a type II cAMP-dependent protein kinase is tightly associated with the fibrous sheath of rat sperm. This unique cytoskeletal structure surrounds the 9+2 axonemal network in the principal piece of the flagellum. Association of the kinase to the fibrous sheath is mediated via its regulatory subunit, RII. An RII-binding...
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