Indomethacin is a potent inhibitor of pristane and plastic disc induced plasmacytomagenesis in a hypersusceptible BALB/c congenic strain.

Article

Indomethacin is a potent inhibitor of pristane and plastic disc induced plasmacytomagenesis in a hypersusceptible BALB/c congenic strain.

Blood - 1 Jul 1997

Potter M, Wax J, Jones G M

Abstract excerpt

Continuous indomethacin (INDO) administration in the drinking water (10 to 20 microg/mL) profoundly inhibited plasmacytoma (PCT) development initiated by three 0.2- or 0.5-mL intraperitoneal (i.p.) injections of pristane in hypersusceptible BALB/c.DBA/2-Idh1-Pep3 congenic mice. The most effective...

Topics

Administration, Oral
Animals
Anti-Inflammatory Agents, Non-Steroidal
Carcinogens
Drug Antagonism
Foreign Bodies
Genetic Predisposition to Disease
Indomethacin
Mice
Mice, Inbred BALB C
Plasmacytoma
Terpenes

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