Article
The Role of Heat Shock Protein, Microbial and Autoimmune Agents in the Aetiology of Behget's Disease
1 Jan 1997
Abstract excerpt
Investigation of the aetiology of Behçet's disease (BD) has focused predominantly on herpes simplex virus immunopathology, autoimmunity to oral mucosa or cross-reactive microbial antigens, and streptococcal infection. These aetiological factors might have a common denominator in microbial heat shock protein (HSP) which shows significant homology with the human mitochondrial HSP. Indeed, the uncommon serotypes of...