Article
Immunology and functional genomics of Behçet's disease.
Cellular and molecular life sciences : CMLS - 1 Sept 2003
Zierhut M, Mizuki N, Ohno S, Inoko H, Gül A, Onoé K, Isogai E
Abstract excerpt
Behçet's disease (BD) is a multisystemic inflammatory disorder. Although the cause and pathogenesis of BD are still unclear, there is evidence for genetic, immunologic and infectious factors at the onset or in the course of BD. This review focuses on the functional genomics and immunology of BD. HLA-B51 is the major disease susceptibility gene locus in BD. An increased number of gammadelta T cells in the...
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