Article
Coxsackievirus-induced chronic inflammatory myopathy: virus variants distinguish between acute cytopathic effects and pathogenesis of chronic disease.
Virology - 23 Jun 1997
Tam P E, Messner R P
Abstract excerpt
Infection with the Tucson strain of coxsackievirus B1 (CVB1T) causes the development of chronic inflammatory myopathy (CIM) and hind limb weakness in susceptible strains of mice. In this study, a panel of six plaque-purified viruses exhibiting either small or large plaque phenotypes was derived f...
Topics
- Animals
- Cell Line
- Chlorocebus aethiops
- Chronic Disease
- Coxsackievirus Infections
- Cytopathogenic Effect, Viral
- Enterovirus B, Human
- Female
- Genetic Variation
- Inflammation
- Mice
- Muscle Weakness
- Myositis
- Protein Biosynthesis
- Receptors, Virus
- Transcription, Genetic
- Virulence