Article
The vitamin D receptor start codon polymorphism (FokI) and bone mineral density in premenopausal American black and white women.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jul 1997
Harris S S, Eccleshall T R, Gross C, Dawson-Hughes B, Feldman D
Abstract excerpt
This study examines the association between bone mineral density (BMD) and a start codon polymorphism (SCP) at the translation initiation site of the vitamin D receptor (VDR) gene. The thymine/cytosine (T/C) polymorphism in the first of two start (ATG) codons can be detected by a restriction fragment length polymorphism (RFLP) using the endonuclease FokI, which recognizes ATG as part of its restriction site. F...
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