Predominant recognition of the ESAT-6 protein in the first phase of interferon with Mycobacterium bovis in cattle

Abstract excerpt

Tuberculosis continues to be a worldwide health problem for both humans and animals. The development of improved vaccines and diagnostic tests requires detailed understanding of the immune responses generated and the antigens recognized during the disease. This study examined the T-cell response which develops in cattle experimentally infected with Mycobacterium bovis. The first significant T-cell response was...

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