Article
The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS.
Cell - 15 Jul 1994
Klaes A, Menne T, Stollewerk A, Scholz H, Klämbt C
Abstract excerpt
The Drosophila gene pointed (pnt) encodes two putative transcription factors (P1 and P2) of the Ets family, which in the embryonic CNS are found exclusively in glial cells. Loss of pnt function leads to poorly differentiated glial cells and a marked decrease in the expression of the neuronal anti...
Topics
- Animals
- Cell Differentiation
- Central Nervous System
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation
- Genes, Insect
- Nerve Tissue Proteins
- Neuroglia
- Neurons
- Phenotype
- Proto-Oncogene Proteins
- RNA, Messenger
- Transcription Factors