Article
Surface expression of low density lipoprotein receptor in EBV-transformed lymphocytes: characterization and use for studying familial hypercholesterolemia.
Atherosclerosis - 1 Jun 1997
Chan P, Jones C, Lafrenière R, Parsons H G
Abstract excerpt
The objectives of the present study were to characterize the surface expression of low density lipoprotein receptor (LDL-R) in Epstein-Barr virus transformed lymphocytes (EBV-L) and to determine the applicability of the cellular system for the study of familial hypercholesterolemia. The EBV-L sub...
Topics
- Adolescent
- Adult
- Aged
- Anticholesteremic Agents
- B-Lymphocytes
- Cell Culture Techniques
- Cell Division
- Cell Membrane
- Cell Transformation, Viral
- Child
- DNA
- Female
- Fibroblasts
- Herpesvirus 4, Human
- Humans
- Hyperlipoproteinemia Type II
- Lovastatin
- Male