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Article

Low density lipoprotein receptor as a candidate receptor for hepatitis C virus

1 Mar 1999

Abstract excerpt

Hepatitis C virus (HCV) binds to different human cell lines in vitro. However, the efficiency of adsorption is very low due mainly to a relatively small fraction of the virus being able to bind to these cells. Free low density lipoprotein (LDL > 200 microg/ml) is able to block the attachment of HCV to human fibroblasts in vitro completely. COS-7 cells being primarily not able to bind HCV were transfected with a...

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PMID: 10022791
DOI: 10.1002/(sici)1096-9071(199903)57:3<223::aid-jmv2>3.0.co;2-4

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